The adenovirus VA RNA-derived miRNAs are not essential for lytic virus growth in tissue culture cells

At late times during a lytic infection human adenovirus type 5 produces ∼10(8) copies per cell of virus-associated RNA I (VA RNAI). This short highly structured RNA polymerase III transcript has previously been shown to be essential for lytic virus growth. A fraction of VA RNAI is processed by Dicer...

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Bibliografiska uppgifter
Huvudupphovsmän: Kamel, Wael, Segerman, Bo, Öberg, Daniel, Punga, Tanel, Akusjärvi, Göran
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2013
Ämnen:
Gene Regulation, Chromatin and Epigenetics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3643585/
https://ncbi.nlm.nih.gov/pubmed/23525465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt172
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