Efficacy of recombinant adenovirus expressing a fusion gene from GM-CSF and Epstein-Barr virus LMP2A in a mouse tumor model

In this study, purified GM-CSF and LMP2A mRNAs were amplified by PCR. Then, the GM-CSF and LMP2A sequences were connected by the polypeptide linker (Gly(4)Ser)(3) using gene splicing by overlap extension. The constructed fusion gene GC2A was inserted into the adenovirus vector. Then the recombinant...

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Bibliographic Details
Published in:Hum Vaccin Immunother
Main Authors: Xue, Qingjie, Li, Xiuzhen, Yang, Chunqing, Ji, Bingyuan, Li, Yunqing, Yan, Yingchun, Yang, Xinxin, Wang, Chunmei, Chen, Ting
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2017
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647964/
https://ncbi.nlm.nih.gov/pubmed/28892414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2017.1356521
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