Efficacy of recombinant adenovirus expressing a fusion gene from GM-CSF and Epstein-Barr virus LMP2A in a mouse tumor model

In this study, purified GM-CSF and LMP2A mRNAs were amplified by PCR. Then, the GM-CSF and LMP2A sequences were connected by the polypeptide linker (Gly(4)Ser)(3) using gene splicing by overlap extension. The constructed fusion gene GC2A was inserted into the adenovirus vector. Then the recombinant...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Xue, Qingjie, Li, Xiuzhen, Yang, Chunqing, Ji, Bingyuan, Li, Yunqing, Yan, Yingchun, Yang, Xinxin, Wang, Chunmei, Chen, Ting
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647964/
https://ncbi.nlm.nih.gov/pubmed/28892414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2017.1356521
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