EB virus-positive tumors are inhibited by rBCG expressing hGM-CSF and LMP2A

For the development of safe and effective EBV (Epstein-Barr virus) vaccines, the Ag85A signal peptide from M. tuberculosis H37Rv was used to construct a recombinant secretory BCG (Bacillus Chalmette-Guérin) plasmid. The Ag85A gene, fused to the EBV LMP2A (latent membrane protein) and hGM-CSF (human...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Yan, Yingchun, Xue, Qing-Jie, Liu, Ang, Wang, Hui, Zhang, Honghua, Wang, Shuang, Zhao, Longyu, Li, Yunqing, Li, Xiuzhen, Yang, Yuanyuan, Chen, Ting, Li, Shigen
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7227694/
https://ncbi.nlm.nih.gov/pubmed/31567046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2019.1670593
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