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Molecular Simulations Suggest a Force-Dependent Mechanism of Vinculin Activation

Focal adhesions are dynamic constructs at the leading edge of migrating cells, linking them to the extracellular matrix and enabling force sensing and transmission. The lifecycle of a focal adhesion is a highly coordinated process involving spatial and temporal variations of protein composition, int...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biophys J
Prif Awduron: Sun, Li, Noel, Jeffrey K., Levine, Herbert, Onuchic, José N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Biophysical Society 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647571/
https://ncbi.nlm.nih.gov/pubmed/29045864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.08.037
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