TGF-β signalling and PEG10 are mutually exclusive and inhibitory in chondrosarcoma cells

Histological distinction between enchondroma and chondrosarcoma is difficult because of a lack of definitive biomarkers. Here, we found highly active transforming growth factor-β (TGF-β) and bone morphogenetic protein (BMP) signalling in human chondrosarcomas compared with enchondromas by immunohist...

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Pubblicato in:Sci Rep
Autori principali: Shinohara, Naohiro, Maeda, Shingo, Yahiro, Yuhei, Sakuma, Daisuke, Matsuyama, Kanehiro, Imamura, Katsuyuki, Kawamura, Ichiro, Setoguchi, Takao, Ishidou, Yasuhiro, Nagano, Satoshi, Komiya, Setsuro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647403/
https://ncbi.nlm.nih.gov/pubmed/29044189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13994-w
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