Suppression of acute and anticipatory nausea by peripherally restricted fatty acid amide hydrolase inhibitor in animal models: role of PPARα and CB(1) receptors

BACKGROUND AND PURPOSE: Effective treatments of nausea are limited. In this study we evaluated the ability of the peripherally restricted fatty acid amide hydrolase (FAAH) inhibitor, URB937, to suppress acute and anticipatory nausea in rats and examined the pharmacological mechanism of this effect....

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Bibliografiska uppgifter
I publikationen:Br J Pharmacol
Huvudupphovsmän: Rock, Erin M, Moreno‐Sanz, Guillermo, Limebeer, Cheryl L, Petrie, Gavin N, Angelini, Roberto, Piomelli, Daniele, Parker, Linda A
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2017
Ämnen:
Research Papers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647182/
https://ncbi.nlm.nih.gov/pubmed/28805944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13980
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