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Suppression of acute and anticipatory nausea by peripherally restricted fatty acid amide hydrolase inhibitor in animal models: role of PPARα and CB(1) receptors

BACKGROUND AND PURPOSE: Effective treatments of nausea are limited. In this study we evaluated the ability of the peripherally restricted fatty acid amide hydrolase (FAAH) inhibitor, URB937, to suppress acute and anticipatory nausea in rats and examined the pharmacological mechanism of this effect....

詳細記述

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書誌詳細
出版年:Br J Pharmacol
主要な著者: Rock, Erin M, Moreno‐Sanz, Guillermo, Limebeer, Cheryl L, Petrie, Gavin N, Angelini, Roberto, Piomelli, Daniele, Parker, Linda A
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647182/
https://ncbi.nlm.nih.gov/pubmed/28805944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13980
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