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Trastuzumab cardiotoxicity: from clinical trials to experimental studies
Epidermal growth factor receptor‐2 (HER‐2) is overexpressed in 20 to 25% of human breast cancers, which is associated with aggressive tumour growth and poor prognosis. Trastuzumab (Herceptin®) is a humanized monoclonal antibody directed against HER‐2, the first highly selective form of therapy targe...
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| Publicado no: | Br J Pharmacol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5647179/ https://ncbi.nlm.nih.gov/pubmed/27714776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13643 |
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