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Definition of hidden drug cardiotoxicity: paradigm change in cardiac safety testing and its clinical implications
Unexpected cardiac adverse effects are the leading causes of discontinuation of clinical trials and withdrawal of drugs from the market. Since the original observations in the mid-90s, it has been well established that cardiovascular risk factors and comorbidities (such as ageing, hyperlipidaemia, a...
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| Publicado no: | Eur Heart J |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6554653/ https://ncbi.nlm.nih.gov/pubmed/29982507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehy365 |
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