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Trastuzumab cardiotoxicity: from clinical trials to experimental studies

Epidermal growth factor receptor‐2 (HER‐2) is overexpressed in 20 to 25% of human breast cancers, which is associated with aggressive tumour growth and poor prognosis. Trastuzumab (Herceptin®) is a humanized monoclonal antibody directed against HER‐2, the first highly selective form of therapy targe...

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Dettagli Bibliografici
Pubblicato in:Br J Pharmacol
Autori principali: Nemeth, Balazs T, Varga, Zoltan V, Wu, Wen Jin, Pacher, Pal
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647179/
https://ncbi.nlm.nih.gov/pubmed/27714776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13643
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