Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca(2+)-Activated K(+) Channels in Pigs

BACKGROUND: Evidence has emerged that small-conductance Ca(2+)-activated K(+) (SK) channels constitute a new target for treatment of atrial fibrillation (AF). SK channels are predominantly expressed in the atria as compared with the ventricles. Various marketed antiarrhythmic drugs are limited by ve...

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Detalhes bibliográficos
Publicado no:Circ Arrhythm Electrophysiol
Main Authors: Diness, Jonas Goldin, Skibsbye, Lasse, Simó-Vicens, Rafel, Santos, Joana Larupa, Lundegaard, Pia, Citerni, Carlotta, Sauter, Daniel Rafael Peter, Bomholtz, Sofia Hammami, Svendsen, Jesper Hastrup, Olesen, Søren-Peter, Sørensen, Ulrik S., Jespersen, Thomas, Grunnet, Morten, Bentzen, Bo Hjorth
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2017
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647113/
https://ncbi.nlm.nih.gov/pubmed/29018164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCEP.117.005125
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