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PML(NLS¯) protein: A novel marker for the early diagnosis of acute promyelocytic leukemia
Promyelocyte leukemia-retinoic acid receptor α (PML-RARα) is known as a fusion gene of acute promyelocytic leukemia (APL). Previous studies have reported that neutrophil elastase (NE) cleaves PML-RARα in early myeloid cells, which leads to the removal of the nuclear localization signal (NLS) in PML...
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| Publicado no: | Mol Med Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5647086/ https://ncbi.nlm.nih.gov/pubmed/28849126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.7272 |
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