Cordycepin promotes apoptosis in renal carcinoma cells by activating the MKK7-JNK signaling pathway through inhibition of c-FLIP(L) expression

Cellular FLICE inhibitory protein (c-FLIP) is a key anti-apoptotic regulator that associates with the signaling complex downstream of NF-κB, negatively interfering with apoptotic signaling. The role of c-FLIP downregulation by negative regulation of NF-κB signaling during apoptosis is poorly underst...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hwang, In-Hu, Oh, Seung Yoon, Jang, Hyun-Jin, Jo, Eunbi, Joo, Jong Cheon, Lee, Kyung-Bok, Yoo, Hwa-Seung, Lee, Mi Young, Park, Soo Jung, Jang, Ik-Soon
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5646797/
https://ncbi.nlm.nih.gov/pubmed/29045468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186489
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