Cordycepin promotes apoptosis by modulating the ERK-JNK signaling pathway via DUSP5 in renal cancer cells

Constitutive activation of extracellular signal regulated kinase (ERK)-Jun NH2-terminal kinase (JNK) signaling commonly occurs in tumors. The activation of ERK promotes cell proliferation, whereas that of JNK induces cell apoptosis. However, the apoptotic mechanism of ERK-JNK signaling in cancer is...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Hwang, Jung-Hoo, Joo, Jong Cheon, Kim, Dae Joon, Jo, Eunbi, Yoo, Hwa-Seung, Lee, Kyung-Bok, Park, Soo Jung, Jang, Ik-Soon
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004077/
https://ncbi.nlm.nih.gov/pubmed/27648363
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