Cordycepin induces apoptosis of human ovarian cancer cells by inhibiting CCL5-mediated Akt/NF-κB signaling pathway

The chemokine, CCL5, is a key mediator for the recruitment of immune cells into tumors and tissues. Akt/NF-κB signaling is significantly activated by CCL5. However, the role of NF-κB inactivation in apoptosis induced by negative regulation of CCL5 remains unclear. Here, we analyzed the effect of cor...

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Detalhes bibliográficos
Publicado no:Cell Death Discov
Main Authors: Cui, Zhen Yang, Park, Soo Jung, Jo, Eunbi, Hwang, In-Hu, Lee, Kyung-Bok, Kim, Sung-Woo, Kim, Dae Joon, Joo, Jong Chun, Hong, Seok Hoon, Lee, Min-Goo, Jang, Ik-Soon
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966410/
https://ncbi.nlm.nih.gov/pubmed/29844932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-018-0063-4
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