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Functional improvement of dystrophic muscle by repression of utrophin: let-7c interaction

Duchenne muscular dystrophy (DMD) is a fatal genetic disease caused by an absence of the 427kD muscle-specific dystrophin isoform. Utrophin is the autosomal homolog of dystrophin and when overexpressed, can compensate for the absence of dystrophin and rescue the dystrophic phenotype of the mdx mouse...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Mishra, Manoj K., Loro, Emanuele, Sengupta, Kasturi, Wilton, Steve D., Khurana, Tejvir S.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5646768/
https://ncbi.nlm.nih.gov/pubmed/29045431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182676
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