Synthesis, Positron Emission Tomography Imaging, and Therapy of Diabody Targeted Drug Lipid Nanoparticles in a Prostate Cancer Murine Model

The blood clearance of chemotherapeutic drugs such as doxorubicin (Dox) can be extended by incorporation into lipid nanoparticles (LNPs) and further improved by tumor targeting with antibody fragments. We used positron emission tomography (PET) imaging in a murine prostate cancer model to evaluate t...

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Detalhes bibliográficos
Publicado no:Cancer Biother Radiopharm
Main Authors: Wong, Patty, Li, Lin, Chea, Junie, Delgado, Melissa K., Poku, Erasmus, Szpikowska, Barbara, Bowles, Nicole, Minnix, Megan, Colcher, David, Wong, Jeffrey Y.C., Shively, John E., Yazaki, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5646751/
https://ncbi.nlm.nih.gov/pubmed/28910151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cbr.2017.2253
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