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Distinct oxysterol requirements for positioning naïve and activated dendritic cells in the spleen

Correct positioning of dendritic cells (DCs) is critical for efficient pathogen encounter and antigen presentation. Epstein-Barr virus–induced gene 2 (EBI2) has been identified as a chemoattractant receptor required for naïve CD4(+)DCIR2(+) DC positioning in response to 7α,25-hydroxycholesterol (7α,...

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Foilsithe in:Sci Immunol
Main Authors: Lu, Erick, Dang, Eric V., McDonald, Jeffrey G., Cyster, Jason G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5646419/
https://ncbi.nlm.nih.gov/pubmed/28738017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aal5237
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