Reprogramming of stromal fibroblasts by SNAI2 contributes to tumor desmoplasia and ovarian cancer progression

BACKGROUND: Molecular profiling in ovarian cancer (OC) revealed that the desmoplasia subtype presented the poorest prognosis, highlighting the contribution of stromal fibroblasts in tumor progression. This study aimed to investigate the molecular characteristics of SNAI2 driving the transcriptional...

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Podrobná bibliografie
Vydáno v:Mol Cancer
Hlavní autoři: Yang, Zongyuan, Yang, Xin, Xu, Sen, Jin, Ping, Li, Xiaoting, Wei, Xiao, Liu, Dan, Huang, Kecheng, Long, Sixiang, Wang, Ya, Sun, Chaoyang, Chen, Gang, Hu, Junbo, Meng, Li, Ma, Ding, Gao, Qinglei
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645935/
https://ncbi.nlm.nih.gov/pubmed/29041931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-017-0732-6
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