Reprogramming of stromal fibroblasts by SNAI2 contributes to tumor desmoplasia and ovarian cancer progression

BACKGROUND: Molecular profiling in ovarian cancer (OC) revealed that the desmoplasia subtype presented the poorest prognosis, highlighting the contribution of stromal fibroblasts in tumor progression. This study aimed to investigate the molecular characteristics of SNAI2 driving the transcriptional...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Yang, Zongyuan, Yang, Xin, Xu, Sen, Jin, Ping, Li, Xiaoting, Wei, Xiao, Liu, Dan, Huang, Kecheng, Long, Sixiang, Wang, Ya, Sun, Chaoyang, Chen, Gang, Hu, Junbo, Meng, Li, Ma, Ding, Gao, Qinglei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645935/
https://ncbi.nlm.nih.gov/pubmed/29041931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-017-0732-6
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