Glial cells are functionally impaired in juvenile neuronal ceroid lipofuscinosis and detrimental to neurons

The neuronal ceroid lipofuscinoses (NCLs or Batten disease) are a group of inherited, fatal neurodegenerative disorders of childhood. In these disorders, glial (microglial and astrocyte) activation typically occurs early in disease progression and predicts where neuron loss subsequently occurs. We h...

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Foilsithe in:Acta Neuropathol Commun
Main Authors: Parviainen, Lotta, Dihanich, Sybille, Anderson, Greg W., Wong, Andrew M., Brooks, Helen R., Abeti, Rosella, Rezaie, Payam, Lalli, Giovanna, Pope, Simon, Heales, Simon J., Mitchison, Hannah M., Williams, Brenda P., Cooper, Jonathan D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2017
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645909/
https://ncbi.nlm.nih.gov/pubmed/29041969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0476-y
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