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Sperm-borne miR-449b influences cleavage, epigenetic reprogramming and apoptosis of SCNT embryos in bovine

Accumulating evidence indicates the absence of paternally derived miRNAs, piwiRNAs, and proteins may be one important factor contributing to developmental failure in somatic cell cloned embryos. In the present study, we found microRNA-449b (miR-449b) was highly expressed in sperm. Target gene predic...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Wang, Mengyun, Gao, Yang, Qu, Pengxiang, Qing, Suzhu, Qiao, Fang, Zhang, Yong, Mager, Jesse, Wang, Yongsheng
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645405/
https://ncbi.nlm.nih.gov/pubmed/29042680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13899-8
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