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Sperm-borne miR-449b influences cleavage, epigenetic reprogramming and apoptosis of SCNT embryos in bovine

Accumulating evidence indicates the absence of paternally derived miRNAs, piwiRNAs, and proteins may be one important factor contributing to developmental failure in somatic cell cloned embryos. In the present study, we found microRNA-449b (miR-449b) was highly expressed in sperm. Target gene predic...

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Foilsithe in:Sci Rep
Main Authors: Wang, Mengyun, Gao, Yang, Qu, Pengxiang, Qing, Suzhu, Qiao, Fang, Zhang, Yong, Mager, Jesse, Wang, Yongsheng
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645405/
https://ncbi.nlm.nih.gov/pubmed/29042680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13899-8
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