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GDC-0449 improves the antitumor activity of nano-doxorubicin in pancreatic cancer in a fibroblast-enriched microenvironment

Pancreatic cancer is one of the most lethal human cancers that currently does not have effective therapies. Novel treatments including nanomedicines and combination therapies are thus urgently needed for these types of deadly diseases. A key feature of pancreatic cancer is its tumor protective dense...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhou, Quan, Zhou, Yongcun, Liu, Xiangrui, Shen, Youqing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645386/
https://ncbi.nlm.nih.gov/pubmed/29042665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13869-0
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