De Novo Lipid Synthesis Facilitates Gemcitabine Resistance Through Endoplasmic Reticulum Stress in Pancreatic Cancer

Pancreatic adenocarcinoma is moderately responsive to gemcitabine-based chemotherapy, the most widely used single agent therapy for pancreatic cancer. While the prognosis in pancreatic cancer remains grim in part due to poor response to therapy, previous attempts at identifying and targeting the res...

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Pubblicato in:Cancer Res
Autori principali: Tadros, Saber B., Shukla, Surendra K., King, Ryan J., Gunda, Venugopal, Vernucci, Enza, Abrego, Jaime, Chaika, Nina V., Yu, Fang, Lazenby, Audrey J., Berim, Lyudmyla, Grem, Jean, Sasson, Aaron R., Singh, Pankaj K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645242/
https://ncbi.nlm.nih.gov/pubmed/28811332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-3062
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