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Therapeutic Targeting of Splicing in Cancer

A number of recent studies have highlighted that splicing is frequently altered in cancer and that mutations affecting splicing of key cancer-associated genes as well as mutations and copy-number changes affecting spliceosomal proteins themselves are enriched in cancer. In parallel, there is also ac...

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Publicat a:Nat Med
Autors principals: Lee, Stanley Chun-Wei, Abdel-Wahab, Omar
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5644489/
https://ncbi.nlm.nih.gov/pubmed/27603132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4165
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