Loading...
A lipid off-switch for mTORC1
Mammalian target of rapamycin complex 1 (mTORC1) is a central regulator of metabolism, cell growth and survival. Our finding that local phosphatidylinositol 3,4-bisphosphate [PI(3,4)P(2)] synthesis at late endosomes/ lysosomes by class II PI3Kβ (PI3KC2β) represses mTORC1 identifies PI3KC2β as a phar...
Na minha lista:
| Udgivet i: | Mol Cell Oncol |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
2017
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5644471/ https://ncbi.nlm.nih.gov/pubmed/29057313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1356899 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|