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Objective measurement and clinical significance of IDO1 protein in hormone receptor-positive breast cancer
BACKGROUND: Immunostimulatory therapies targeting immune-suppressive pathways produce durable responses in advanced solid tumors. Indoleamine 2,3-dioxygenase (IDO) is the rate-limiting oxidoreductase that catalyzes the degradation of tryptophan to kynurenine. IDO induces immune tolerance by downregu...
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| Publicado no: | J Immunother Cancer |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5644103/ https://ncbi.nlm.nih.gov/pubmed/29037255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-017-0285-7 |
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