Objective measurement and clinical significance of IDO1 protein in hormone receptor-positive breast cancer

BACKGROUND: Immunostimulatory therapies targeting immune-suppressive pathways produce durable responses in advanced solid tumors. Indoleamine 2,3-dioxygenase (IDO) is the rate-limiting oxidoreductase that catalyzes the degradation of tryptophan to kynurenine. IDO induces immune tolerance by downregu...

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Bibliografische gegevens
Gepubliceerd in:J Immunother Cancer
Hoofdauteurs: Carvajal-Hausdorf, Daniel E., Mani, Nikita, Velcheti, Vamsidhar, Schalper, Kurt A., Rimm, David L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2017
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5644103/
https://ncbi.nlm.nih.gov/pubmed/29037255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-017-0285-7
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