Ottogi Inhibits Wnt/β-catenin Signaling by Regulating Cell Membrane Trafficking of Frizzled8

Wnt signaling controls critical developmental processes including tissue/body patterning. Here we report the identification of a novel regulator of Wnt signaling, OTTOGI (OTG), isolated from a large-scale expression screening of human cDNAs in zebrafish embryos. Overexpression of OTG in zebrafish em...

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Vydáno v:Sci Rep
Hlavní autoři: Kim, Hyun-Taek, Lee, Mi-Sun, Jeong, Yun-Mi, Ro, Hyunju, Kim, Dong-Il, Shin, Yong-Hwan, Kim, Ji-Eun, Hwang, Kyu-Seok, Choi, Jung-Hwa, Bahn, Minjin, Lee, Jeong-Ju, Lee, Sang H., Bae, Young-Ki, Lee, Jin-Soo, Choi, Joong-Kook, Kim, Nam-Soon, Yeo, Chang-Yeol, Kim, Cheol-Hee
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643531/
https://ncbi.nlm.nih.gov/pubmed/29038508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13429-6
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