A novel immunohistochemical score to predict early mortality in acute myeloid leukemia patients based on indoleamine 2,3 dioxygenase expression

Indoleamine 2,3 dioxygenase-1 (IDO-1) is an enzyme in the kynurenine pathway which augments tumor-induced immune tolerance. Previous studies in childhood acute myeloid leukemia (AML) have shown a negative correlation of IDO-1 mRNA expression with outcomes. The aim of our study was to develop a pract...

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Publicado no:Sci Rep
Main Authors: Mangaonkar, Abhishek, Mondal, Ashis Kumar, Fulzule, Sadanand, Pundkar, Chetan, Park, Eun Jeong, Jillella, Anand, Kota, Vamsi, Xu, Hongyan, Savage, Natasha M., Shi, Huidong, Munn, David, Kolhe, Ravindra
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643528/
https://ncbi.nlm.nih.gov/pubmed/29038460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12940-0
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