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A novel immunohistochemical score to predict early mortality in acute myeloid leukemia patients based on indoleamine 2,3 dioxygenase expression
Indoleamine 2,3 dioxygenase-1 (IDO-1) is an enzyme in the kynurenine pathway which augments tumor-induced immune tolerance. Previous studies in childhood acute myeloid leukemia (AML) have shown a negative correlation of IDO-1 mRNA expression with outcomes. The aim of our study was to develop a pract...
Αποθηκεύτηκε σε:
Τόπος έκδοσης: | Sci Rep |
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Κύριοι συγγραφείς: | , , , , , , , , , , , |
Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
Nature Publishing Group UK
2017
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5643528/ https://ncbi.nlm.nih.gov/pubmed/29038460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12940-0 |
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