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A novel Fer/FerT targeting compound selectively evokes metabolic stress and necrotic death in malignant cells

Disruption of the reprogrammed energy management system of malignant cells is a prioritized goal of targeted cancer therapy. Two regulators of this system are the Fer kinase, and its cancer cell specific variant, FerT, both residing in subcellular compartments including the mitochondrial electron tr...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Elkis, Yoav, Cohen, Moshe, Yaffe, Etai, Satmary-Tusk, Shirly, Feldman, Tal, Hikri, Elad, Nyska, Abraham, Feiglin, Ariel, Ofran, Yanay, Shpungin, Sally, Nir, Uri
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643328/
https://ncbi.nlm.nih.gov/pubmed/29038547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00832-w
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