Loss of TMF/ARA160 Protein Renders Colonic Mucus Refractory to Bacterial Colonization and Diminishes Intestinal Susceptibility to Acute Colitis

TMF/ARA160 is a Golgi-associated protein with several cellular functions, among them direction of the NF-κB subunit, p65 RelA, to ubiquitination and proteasomal degradation in stressed cells. We sought to investigate the role of TMF/ARA160 under imposed stress conditions in vivo. TMF(−/−) and wild-t...

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Detaylı Bibliyografya
Asıl Yazarlar: Bel, Shai, Elkis, Yoav, Lerer-Goldstein, Tali, Nyska, Abraham, Shpungin, Sally, Nir, Uri
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2012
Konular:
Immunology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408173/
https://ncbi.nlm.nih.gov/pubmed/22553199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.364786
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