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The dock-and-coalesce mechanism for the association of a WASP disordered region with the Cdc42 GTPase

Intrinsically disordered proteins (IDPs) play key roles in signaling and regulation. Many IDPs undergo folding upon binding to their targets. We have proposed that coupled folding and binding of IDPs generally follow a dock-and-coalesce mechanism, whereby a segment of the IDP, through diffusion, doc...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:FEBS J
Prif Awduron: Ou, Li, Matthews, Megan, Pang, Xiaodong, Zhou, Huan-Xiang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643242/
https://ncbi.nlm.nih.gov/pubmed/28805312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.14197
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