Inhibition of CUG-binding protein 1 and activation of caspases are critically involved in piperazine derivative BK10007S induced apoptosis in hepatocellular carcinoma cells

Though piperazine derivative BK10007S was known to induce apoptosis in pancreatic cancer xenograft model as a T-type CaV3.1 a1G isoform calcium channel blocker, its underlying antitumor mechanism still remains unclear so far. Thus, in the present study, the antitumor mechanism of BK10007S was elucid...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Kim, Ju-Ha, Kwon, Hee Young, Ryu, Dong Hoon, Nam, Min-Ho, Shim, Bum Sang, Kim, Jin Han, Lee, Jae Yeol, Kim, Sung-Hoon
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643113/
https://ncbi.nlm.nih.gov/pubmed/29036189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186490
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