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Iterative Molecular Dynamics – Rosetta Membrane Protein Structure Refinement Guided by Cryo-EM Densities

Knowing atomistic details of proteins is essential not only for the understanding of protein function but also for the development of drugs. Experimental methods such as X-ray crystallography, NMR and cryo-EM are the preferred form of protein structure determination and have achieved great success o...

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Bibliografische gegevens
Gepubliceerd in:J Chem Theory Comput
Hoofdauteurs: Leelananda, Sumudu P., Lindert, Steffen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642286/
https://ncbi.nlm.nih.gov/pubmed/28949136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.7b00464
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