Pharmacokinetics of orally administered low-dose rapamycin in healthy dogs: A pilot study

OBJECTIVE: To determine the pharmacokinetics of orally administered rapamycin in healthy dogs. ANIMALS: 5 healthy purpose-bred hounds. PROCEDURES: The study consisted of 2 experiments. In experiment 1, each dog received rapamycin (0.1 mg/kg, PO) once; blood samples were obtained immediately before a...

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Detalhes bibliográficos
Publicado no:Am J Vet Res
Main Authors: Larson, Jeanne C., Allstadt, Sara D., Fan, Timothy M., Khanna, Chand, Lunghofer, Paul J., Hansen, Ryan J., Gustafson, Daniel L., Legendre, Alfred M., Galyon, Gina D., LeBlanc, Amy K., Martin-Jimenez, Tomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642271/
https://ncbi.nlm.nih.gov/pubmed/26709938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2460/ajvr.77.1.65
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