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Pharmacokinetics of Cyclophosphamide after Oral and Intravenous Administration to Dogs with Lymphoma
BACKGROUND: Cyclophosphamide is an alkylating chemotherapeutic drug administered IV or PO. It is currently assumed that exposure to the active metabolite, 4-hydroxycyclophosphamide (4-OHCP), is the same with either route of administration. OBJECTIVES: To characterize the pharmacokinetics of cyclopho...
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Publicado no: | J Vet Intern Med |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4331015/ https://ncbi.nlm.nih.gov/pubmed/21564295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1939-1676.2011.0730.x |
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