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Pharmacokinetics of Cyclophosphamide after Oral and Intravenous Administration to Dogs with Lymphoma

BACKGROUND: Cyclophosphamide is an alkylating chemotherapeutic drug administered IV or PO. It is currently assumed that exposure to the active metabolite, 4-hydroxycyclophosphamide (4-OHCP), is the same with either route of administration. OBJECTIVES: To characterize the pharmacokinetics of cyclopho...

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Detalhes bibliográficos
Publicado no:J Vet Intern Med
Main Authors: Warry, E., Hansen, R. J., Gustafson, D. L., Lana, S. E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331015/
https://ncbi.nlm.nih.gov/pubmed/21564295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1939-1676.2011.0730.x
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