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Programmed serial stereochemical relay and its application in the synthesis of morphinans

Herein we report a rationally designed, serial point-to-axial and axial-to-point stereoinduction and its integration into multi-step and target-oriented organic synthesis. In this proof-of-concept study, the configurational stability of several carefully designed atropisomeric intermediates and the...

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Publicat a:Chem Sci
Autors principals: Ho (Kenny) Park, Kun, Chen, Rui, Chen, David Y.-K.
Format: Artigo
Idioma:Inglês
Publicat: Royal Society of Chemistry 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642196/
https://ncbi.nlm.nih.gov/pubmed/29147530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc03189k
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