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Synthesis of Morphinan Alkaloids in Saccharomyces cerevisiae
Morphinan alkaloids are the most powerful narcotic analgesics currently used to treat moderate to severe and chronic pain. The feasibility of morphinan synthesis in recombinant Saccharomyces cerevisiae starting from the precursor (R,S)-norlaudanosoline was investigated. Chiral analysis of the reticu...
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| Pubblicato in: | PLoS One |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4408053/ https://ncbi.nlm.nih.gov/pubmed/25905794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124459 |
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