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Synthesis of Morphinan Alkaloids in Saccharomyces cerevisiae
Morphinan alkaloids are the most powerful narcotic analgesics currently used to treat moderate to severe and chronic pain. The feasibility of morphinan synthesis in recombinant Saccharomyces cerevisiae starting from the precursor (R,S)-norlaudanosoline was investigated. Chiral analysis of the reticu...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4408053/ https://ncbi.nlm.nih.gov/pubmed/25905794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124459 |
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