Ascorbic acid alters cell fate commitment of human neural progenitors in a WNT/β-catenin/ROS signaling dependent manner

BACKGROUND: Improving the neuronal yield from in vitro cultivated neural progenitor cells (NPCs) is an essential challenge in transplantation therapy in neurological disorders. In this regard, Ascorbic acid (AA) is widely used to expand neurogenesis from NPCs in cultures although the mechanisms of i...

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Dettagli Bibliografici
Pubblicato in:J Biomed Sci
Autori principali: Rharass, Tareck, Lantow, Margareta, Gbankoto, Adam, Weiss, Dieter G., Panáková, Daniela, Lucas, Stéphanie
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641995/
https://ncbi.nlm.nih.gov/pubmed/29037191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-017-0385-1
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