Ascorbic acid alters cell fate commitment of human neural progenitors in a WNT/β-catenin/ROS signaling dependent manner

BACKGROUND: Improving the neuronal yield from in vitro cultivated neural progenitor cells (NPCs) is an essential challenge in transplantation therapy in neurological disorders. In this regard, Ascorbic acid (AA) is widely used to expand neurogenesis from NPCs in cultures although the mechanisms of i...

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Dades bibliogràfiques
Publicat a:J Biomed Sci
Autors principals: Rharass, Tareck, Lantow, Margareta, Gbankoto, Adam, Weiss, Dieter G., Panáková, Daniela, Lucas, Stéphanie
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641995/
https://ncbi.nlm.nih.gov/pubmed/29037191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-017-0385-1
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