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The dual role of poly(ADP-ribose) polymerase-1 in modulating parthanatos and autophagy under oxidative stress in rat cochlear marginal cells of the stria vascularis

Oxidative stress is reported to regulate several apoptotic and necrotic cell death pathways in auditory tissues. Poly(ADP-ribose) polymerase-1 (PARP-1) can be activated under oxidative stress, which is the hallmark of parthanatos. Autophagy, which serves either a pro-survival or pro-death function,...

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Enregistré dans:
Détails bibliographiques
Publié dans:Redox Biol
Auteurs principaux: Jiang, Hong-Yan, Yang, Yang, Zhang, Yuan-Yuan, Xie, Zhen, Zhao, Xue-Yan, Sun, Yu, Kong, Wei-Jia
Format: Artigo
Langue:Inglês
Publié: Elsevier 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641921/
https://ncbi.nlm.nih.gov/pubmed/29049980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.10.002
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