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Liquidizing FUS via prion‐like domain phosphorylation
FUS is an RNA‐binding protein (RBP) with a prion‐like domain (PrLD) that condenses into functional liquids, which can aberrantly phase transition into solid aggregates comprised of pathological fibrils connected to neurodegenerative disease. How cells prevent aberrant phase transitions of FUS and ot...
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| Udgivet i: | EMBO J |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5641903/ https://ncbi.nlm.nih.gov/pubmed/28963393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201798078 |
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