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AB086. HLA-B*1502 and HLA-B*5801 genotyping for the prevention of severe cutaneous adverse drug reactions in a Children’s Hospital

BACKGROUND: Severe cutaneous adverse drug reactions (SCARs) are life-threatening. This includes Stevens-Johnson syndrome (SJS) and the more severe phenotype, toxic epidermal necrolysis (TEN). Clinical studies have shown that HLA-B*1502 allele is strongly associated with carbamazepine (CBZ) induced S...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Ann Transl Med
Prif Awduron: Ching, Leng Kee, Low, Wendy, Tan, Yuen Ming
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: AME Publishing Company 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641803/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2017.s086
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