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AB086. HLA-B*1502 and HLA-B*5801 genotyping for the prevention of severe cutaneous adverse drug reactions in a Children’s Hospital
BACKGROUND: Severe cutaneous adverse drug reactions (SCARs) are life-threatening. This includes Stevens-Johnson syndrome (SJS) and the more severe phenotype, toxic epidermal necrolysis (TEN). Clinical studies have shown that HLA-B*1502 allele is strongly associated with carbamazepine (CBZ) induced S...
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| Publicado no: | Ann Transl Med |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
AME Publishing Company
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5641803/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2017.s086 |
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