The influence of two functional genetic variants of GRK5 on tau phosphorylation and their association with Alzheimer's disease risk

Our work explores the relationship between G protein-coupled receptor kinase-5 (GRK5) single nucleotide polymorphisms and Alzheimer's disease risk. We confirmed that GRK5 translocates from the cellular membrane to the cytosol in the hippocampus of Alzheimer's disease mice and that GRK5 def...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhang, Yuan, Zhao, Jianghao, Yin, Mingkang, Cai, Yujie, Liu, Shengyuan, Wang, Yan, Zhang, Xingliang, Cao, Hao, Chen, Ting, Huang, Pengru, Mai, Hui, Liu, Zhou, Tao, Hua, Zhao, Bin, Cui, Lili
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641163/
https://ncbi.nlm.nih.gov/pubmed/29069820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20283
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