Acquired somatic TP53 or PIK3CA mutations are potential predictors of when polyps evolve into colorectal cancer

Colorectal cancer (CRC) develops from accumulated mutations. However, which gene determines the malignant transformation from adenoma to carcinoma is still uncertain. Fifty-three formalin fixed paraffin-embedded polyps that had pathological findings from patients with hyperplasia, adenomatous, and t...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Chang, Pi-Yueh, Chen, Jinn-Shiun, Chang, Shih-Cheng, Wang, Mei-Chia, Chang, Nai-Chung, Wen, Ying-Hao, Tsai, Wen-Sy, Liu, Wei-Hsiu, Liu, Hsiu-Ling, Lu, Jang-Jih
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641135/
https://ncbi.nlm.nih.gov/pubmed/29069792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20376
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