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Acquired somatic TP53 or PIK3CA mutations are potential predictors of when polyps evolve into colorectal cancer

Colorectal cancer (CRC) develops from accumulated mutations. However, which gene determines the malignant transformation from adenoma to carcinoma is still uncertain. Fifty-three formalin fixed paraffin-embedded polyps that had pathological findings from patients with hyperplasia, adenomatous, and t...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Chang, Pi-Yueh, Chen, Jinn-Shiun, Chang, Shih-Cheng, Wang, Mei-Chia, Chang, Nai-Chung, Wen, Ying-Hao, Tsai, Wen-Sy, Liu, Wei-Hsiu, Liu, Hsiu-Ling, Lu, Jang-Jih
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641135/
https://ncbi.nlm.nih.gov/pubmed/29069792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20376
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