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Direct comparison study of DNA methylation markers in EpCAM-positive circulating tumour cells, corresponding circulating tumour DNA, and paired primary tumours in breast cancer

Circulating Tumour Cells (CTCs) and circulating tumour DNA (ctDNA) represent a non-invasive liquid biopsy approach for the follow-up and therapy management of cancer patients. We evaluated whether DNA methylation status in CTCs and ctDNA is comparable and whether it reflects the status of primary tu...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Chimonidou, Maria, Strati, Areti, Malamos, Nikos, Kouneli, Sophia, Georgoulias, Vassilis, Lianidou, Evi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641111/
https://ncbi.nlm.nih.gov/pubmed/29069768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18679
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